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Pitt Innovators Issued 6 Patents in September 2021

Posted on October 7, 2021 by Mike Yeomans

 

The University of Pittsburgh announced that Pitt innovators were issued 6 U.S. patents in September 2021.

Featured Patent: 11,129,846 “Method of Treating Severe Asthma”

Severe asthma accounts for 5-10 percent of asthma sufferers, but consumes up to 50 percent of asthma-related healthcare costs of $28 billion per year. Corticosteroids, a mainstay of asthma therapy, are ineffective at treating severe asthma, leading to more frequent emergency care and hospitalization. The innovators have shown that expression of IFN-y is significantly reduced in IRF5-deficient mice. An intervention to block IRF5 function in the lungs of severe asthmatics is therefore a promising new therapeutic modality by preventing airway hyperactivity.

For more information on this technology, contact Maria Vanegas at mvanegas@innovation.pitt.edu.

Below is a list of patents issued to Pitt innovators in Septembert 2021. You can also search the complete database of all Pitt innovations available for licensing.

Patent
Number

Title

 

Inventor(s)

 

Licensing Manager

 

     Status

 

 

 

 

 

 

 

 

11,111,253

6-ARYL-7 Substituted-3-(1H-PYRAZOL-5-YL)-7-H-[1,2,4] TRIAZOLO [3,4-B] [1,3,4] Thiadiazines as Inhibitors of the Stat3 Pathway with Anti-Proliferative Activity

 

Donna Huryn; Peter Wipf; Jennifer Grandis; Matthew LaPorte; Paul Johnston; Mark Schurdak; Raffaele Colombo

 

Maria Vanegas

 

Available for licensing

 

 

 

 

 

 

 

 

11,117,936

Affinity-Enhanced Monomeric Streptavidin Chimeric Antigen Receptor (CAR)

 

Jason Lohmueller

 

Andrew Remes

 

Available for licensing

 

 

 

 

 

 

 

 

11,123,454

Biodegradable, Thermally Responsive Injectable Hydrogel for Treatment of Ischemic Cardiomyopathy

 

Tomo Yoshizumi; William Wagner; Yang Zhu; Hongbin Jiang

 

Janice Panza

 

Available for licensing

 

 

 

 

 

 

 

 

11,129,711

Double Component Mandrel for Electrospun Stentless, Multi-Leaflet Valve Fabrication

 

Antonio D’Amore; William Wagner; Vinay Badhwar; Young Jae Chun

 

Janice Panza

 

Licensed

 

 

 

 

 

 

 

 

11,129,875

Osteoarthritis Treatment with Chemokine-Loaded Alginate Microparticles

 

Riccardo Gottardi; Steven Little; Daniel Desantis; Mintai Hwang

 

Janice Panza

 

Available for licensing

 

 

 

 

 

 

 

 

11,129,846

Method of Treating Severe Asthma

 

Anuradha Ray; Timothy Oriss; Prabir Ray; Sally Wenzel

 

Maria Vanegas

 

Available for licensing

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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