University of Pittsburgh Announces Four U.S. Patents Issued to Pitt Innovators in July 2025

Pitt innovators were issued 4 U.S. patents in July 2025.

Featured patent: 12,371,463: Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections

Pitt innovators have identified a novel approach to combat antibiotic resistance in Gram-negative bacterial pathogens using cationic peptides. Additionally, this research provides a detailed map of the genetic pathways involved in resistance, which can be leveraged to design combination therapies that prevent or delay the emergence of resistance. The findings also open up new avenues for developing diagnostic tools to rapidly identify bacterial strains that remain susceptible to these peptides, thereby improving the effectiveness of treatment regimens. The research behind this discovery is supported by robust in vitro data, utilizing experimental evolution and whole-population genome sequencing to track the genetic changes leading to resistance. For more information on this technology, including licensing, contact us at partner@pitt.edu.

Below is a listing of all patents issued to Pitt innovators in June 2025. You can also search all Pitt technologies available for licensing.